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Identification of Novel Regulatory Mechanisms and Therapeutic Targets for Treating Spinal Cord Injury

Lead Physician: Jiaqian Wu, Ph.D.

New regulatory mechanisms and molecular targets for spinal cord injury are being identified using gene transcription profiling, computational analysis and functional assays. The researchers have identified a new class of potential therapeutic targets – long noncoding RNAs – in oligodendrocyte precursor formation from neural stem cells. RNA-based therapeutics represent promising new strategies for treating neurological disorders.