Gene Transcription and Regulation of Stem Cell Differentiation
Lead Physician: Jia Quan Wu, Ph.D.
This research combines stem cell biology and systems-based
approaches involving genomics, proteomics, bioinformatics and functional assays
to unravel gene transcription and regulatory mechanisms governing stem cell
One major focus is investigating stem cell neural
differentiation and developing effective and safe treatment for spinal cord
injury and neurological diseases such as stroke.
The other area lies in the
studies of the regulatory networks of hematopoietic precursor cell self-renewal
and differentiation using the multipotent EML (erythroid, myeloid and
lymphocytic) cell as a model system.