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Optimization of tissue engineering matrices for SCI treatment

Lead Physician: Laura Smith Callahan, Ph.D.

The study aims to determine the optimal Young’s Modulus and concentration of laminin (IKVAV) and  n-cadherin (HAVDI) peptides on maturation of human induced pluripotent stem cell derived neural stem cells toward mature neurons in 2D culture on  continuous gradient polyethylene glycol hydrogels.